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KMID : 0377619730240060645
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Korean Jungang Medical Journal
1973 Volume.24 No. 6 p.645 ~ p.651
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Glucose Tolerance in Crainiocerebral Injury
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Abstract
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The investigation was undertaken to determine glucose tolerance in uncomplicated craniocerebral injury in man.
Observation was made on 50 patients with craniocerebral injury admitted to the Department of Neurosurgery, Korea University College of Medicine from February ´72 to September ´72.
In order to assess glucose tolerance as influenced by degree of craniocerebral injury and by time sequent to injury, test was carried out with the patients grouped into four according to the degree of the mental affection.
Intravenous glucose tolerance test was carried out with administration of 50 cc of 505% glusose intravenously over a 2 to 3 minute period. Glucose tolerance was compared among the trauma groups and among the periods by blood sugar disappearance rate (K values) and elevations of the disappearance curves after glucose loading. Covariance analysis was used to compare the regression K values and heights".
In summary, immediately after injury (2-3 days) the mean blood sugar level was increased in all patients in comparison with that of follow-up(14-15 days).
With increase in degree of injury, there are higher post-loading glucose levels, and the disappearance rates was decreased.
As time increased after injury, the disappearance rate improved along with the decrease of blood sugar level to normal.
The glucose disappearance rate in patients,; group II, associated with subarachnoid hemorrhage was decreased more than that in the same group of patients who were not associated with subarachnoid hemorrhage.
There was evidence that glucose intolerance was resulted from injuries and that the degree of intolerance was directly related to the extent of trauma or stress and returns to normal during or after healing.
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KEYWORD
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